Abstract
Primary central nervous system lymphoma (PCNSL) is rare, although its frequency has increased in recent years. Radiographically, almost all PCNSL enhance on CT and/or MRI, and nonenhancing PCNSL has been thought to be extremely rare. We present PCNSL showing multiple nonenhancing lesions on MRI in an immunocompetent patient.
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Hochberg FH, Miller DC (1988) Primary central nervous lymphoma. J Neurosurg 68:835–853
Eby NL, Grufferman S, Flannelly CM, Schold SC Jr, Vogel FS, Burger PC (1988) Increasing incidence of primary brain lymphoma in the US. Cancer 62: 2461–2465
O'Neill BP, Illig JJ (1989) Primary central nervous system lymphoma. Mayo Clin Proc 64:1005–1020
Roman-Goldstein SM, Goldman DL, Howieson J, Belkin R, Neuwelt EA (1992) MR of primary CNS lymphoma in immunologically normal patients. AJNR 13:1207–1213
Lee Y-Y, Bruner JM, Tassel PV, Libshitz HI (1986) Primary central nervous system lymphoma: CT and pathologic correlation. AJNR 7:599–604
Poon T, Matoso I, Techertkoff V, Weitzner I Jr, Gade M (1989) CT features of primary cerebral lymphoma in AIDS and non-AIDS patients. J Comput Assist Tomogr 13:6–9
DeAngelis LM (1993) Cerebral lymphoma presenting as a nonenhancing lesion on computed tomographic/magnetic resonance scan. Ann Neurol 33: 308–311
Ebhardt G, Meese W (1977) Malignant lymphomas of the brain. In: Wüllenweber R, Brock M, Hamer J, Klinger M, Spoerri O (eds) Advances in neurosurgery, vol 4. Springer, Berlin Heidelberg New York, pp 303–308
Tadmor R, Davis KR, Roberson GH, Kleinman GM (1978) Computed tomography in primary malignant lymphoma of the brain. J Comput Assist Tomogr 2:135–140
Cellerier P, Chiras J, Gray F, Metzger J, Bories J (1984) Computed tomography in primary lymphoma of the brain. Neuroradiology 26:485–492
Sieb JP, Roost D van, Solymosi L (1992) Zerebrales B-Zell-Lymphom mit dem neuroradiologischen Bild einer multifokalen Leukenzephalopathie. Fortschr Röntgenstr 156:503–504
Bogdahn U, Bogdahn S, Mertens HG, Dommasch D, Wodarz R, Wünsch PH, Kühl P, Richter E (1986) Primary non-Hodgkin's lymphomas of the CNS. Acta Neurol Scand 73:602–614
Jack CR Jr, O'Neill BP, Banks PM, Reese DF (1988) Central nervous system lymphoma: histologic types and CT appearance. Radiology 167:211–215
Vaquero J, Martínez R, Rossi E, López R (1984) Primary cerebral lymphoma: the “ghost tumor”. J Neurosurg 60:174–176
Houthoff HJ, Poppema S, Ebels EJ, Elema JD (1978) Intracranial malignant lymphomas: a morphologic and immunocytologic study of twenty cases. Acta Neuropathol (Berl) 44:203–210
Shibata S (1989) Sites of origin of primary intracerebral malignant lymphoma. Neurosurgery 25:14–19
Watanabe M, Tanaka R, Takeda N, Wakabayashi K, Takahashi H (1992) Correlation of computed tomography with the histopathology of primary malignant lymphoma of the brain. Neuroradiology 34:36–42
Thomas M, Macpherson P (1982) Computed tomography of intracranial lymphoma. Clin Radiol 33:331–336
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Terae, S., Ogata, A. Nonenhancing primary central nervous system lymphoma. Neuroradiology 38, 34–37 (1996). https://doi.org/10.1007/BF00593213
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DOI: https://doi.org/10.1007/BF00593213