Summary
An index, α = (Δr/r)/(ΔR/R), is proposed for assessment of the relative degree of participation of a regional flow resistance in a blood pressure reflex, wherer andR are regional and total peripheral resistances respectively and Δ's refer to their reflexive changes. For actual computation, α =I (iΔP − PΔi)/i(IΔP − PΔI), whereI=cardiac output,i=regional flow rate,P=mean arterial pressure. When the change in cardiac output is neglegible, the above equation is simplified as Δ=1 − PΔi/iΔP. Another index,β = Δg/ΔG = (PΔi − iΔP)/(PΔI − IΔP), is introduced for the degree of contribution of a region to a reflex, whereg andG are regional and total conductances.αi = β1. Some examples of application of the indices are presented.
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Brind, S. H., J. R. Bianchine, andM. N. Levy: Effect of bilateral occlusion of common carotid arteries on cardiac output and oxygen content of arterial and venous blood in the anesthetized dog. Amer. J. Physiol.185, 483–486 (1956).
Burton, A. C.: Physiology and biophysics of the circulation. Chicago: Year Book Medical Publ. 1965.
Corcondilas, A., D. E. Donald, andJ. T. Shepherd: Assessment by two independent methods of the role of cardiac output in the pressor response to carotid occlusion. J. Physiol. (Lond.)170, 250–262 (1964).
Green, H. D.: Circulatory system: physical principles. In: Medical Physics (ed.O. Glasser), vol. 2. Chicago: Year Book Publ. 1950.
Kenney, R. A., E. Neil, andA. Schweitzer: Carotid sinus reflexes and cardiac output in dogs. J. Physiol. (Lond.)114, 27–40 (1951).
Polosa, C., andG. Rossi: Cardiac output and peripheral blood flow during occlusion of carotid arteries. Amer. J. Physiol.200, 1185–1190 (1961).
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Supported in part by a grant from the Ministry of Education of Japan.
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Iriuchijima, J., Koike, H. & Matsuda, K. Indices for the role played by regional flow resistance in blood pressure reflex. Pflugers Arch. 307, 22–28 (1969). https://doi.org/10.1007/BF00589456
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DOI: https://doi.org/10.1007/BF00589456