Abstract
Localisation of spinal cord lesions by MRI was correlated with neurological symptoms and signs in 16 patients with clinical and laboratory evidence of multiple sclerosis. There was good correspondence between spinal cord lesions and motor tract signs. On the other hand, superficial or deep sensory disturbances correlated with spinal cord lesions in only about a quarter of the patients. MRI of the spinal cord appeared to explain the myelopathy in 11 patients, while in 3 there was strong clinical evidence of more extensive demyelinating lesions. In 7 of the 16 patients MRI of the brain was normal.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Poser CM (1981) Diseases of the myelin sheath. In: Baker AB (ed) Clinical neurology. Harper and Row, Philadelphia, vol II, ch 25
Adams CWM (1983) The general pathology of multiple sclerosis: morphological and chemical aspects of the lesions. In: Hallpike IF, Adams CWM, Tourtellotte WW (eds) Multiple sclerosis. Chapman and Hall, London, pp 203–240
Mastaglia FL, Black JL, Cala LA, Collins DWK (1977) Evoked potentials, saccadic velocities and computerised tomography in diagnosis of multiple sclerosis. Br Med J i:1315–1317
Namerow N (1968) Circardian temperature rhythm and vision in multiple sclerosis. Neurology 18:417–422
Ormerod IEC, Miller DH, McDonald WI et al (1987) The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions. A quantitative study. Brain 110: 1579–1616
Li D, Mayo J, Fache S et al (1984) Lack of correlation between clinical manifestations and lesions of MS seen by NMR. Neurology 34 (Suppl 1):136
Scotti G, Scialfa G, Biondi A et al (1986) Magnetic resonance in multiple sclerosis. Neuroradiology 28:319–323
Grossman RI, Braffman BH, Brorson JR et al (1988) Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. Radiology 169:117–122
Rasminsky M (1973) The effects of temperature on conduction in demyelinated single nerve fibers. Arch Neurol 28:287–292
Davis F, Becker F, Michael J, Sorensen L (1970) Effects of intravenous sodium bicarbonate, disodium edetate and hyperventilation on visual and oculomotor signs in multiple sclerosis. J Neurol Neurosurg Psychiatry 33:723–732
Maravilla KR, Weinreb JC, Suss R, Nunnally RL (1985) Magnetic resonance demonstration of multiple sclerosis plaques in the cervical cord. AJR 144:381–385
Miller DH, McDonald WI, Johnson G et al (1987) Detection of intrinsic inflammatory and demyelinating spinal cord lesions with MRI. Society of Magnetic Resonance in Medicine, Sixth Annual Meeting (abstract), p 9
Barakos JA, Mark SA, Dillon WP, Norman D (1990) MR imaging of acute transverse myelitis and AIDS myelopathy. J Comput Assist Tomogr 14:45–50
DeLaPaz RL (1990) Demyelinating disease of the spinal cord. In: Enzmann DR, DeLaPaz RL, Rubin JB (eds) Magnetic resonance of the spine. Mosby, St. Louis, pp 423–436
Nilsson O, Larsson EM, Holtas S (1987) Myelopathy patients studied with magnetic resonance for multiple sclerosis plaques. Acta Neurol Scand 76:272–277
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Papadopoulos, A., Gatzonis, S., Gouliamos, A. et al. Correlation between spinal cord MRI and clinical features in patients with demyelinating disease. Neuroradiology 36, 130–133 (1994). https://doi.org/10.1007/BF00588078
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00588078