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Zum Mechanismus der ökonomischen Halteleistung eines glatten Muskels (Byssus retractor anterior,Mytilus edulis)

The mechanism of high ‘holding economy’ in a smooth muscle

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Summary

Freeze-dried fibre-bundles (GF) of the anterior byssus retractor muscle (ABRM) ofMytilus develop in Ca2+-containing ATP-salt-solution almost the same isometric tension as the surviving muscle and maintain the same tension remnant when Ca2+ is deprived. The ratio ATPase/tension of Ca2+-activated GF (0.15 mcal/sec × kg tension × cm fibre at 20°C, determined from ATPase measurements) corresponds to the heat of maintenance of living muscle in tetanus (0.07 mcal/see × kg × cm), while it is nearly zero when GF are in the “catch” state in Ca2+-free solution.

Contrary to isometric tension and tension remnant, the energy expenditure and speed of tension development depend on temperature (Q 10≈3); moreover the ratio ATPase/tension of Ca2+-activated GF decreases to 70% as the extent of the “caught” state increases in the course of three successive periods of contraction. But it increases again to the former level when the catch is abolished.

These findings are discussed in relation to the “Paramyosin-theory” of catch. With regard to the typical ultrastructure of caught muscle fibres it is suggested that their increased economy is based on interaction of the thick paramyosinfilaments.

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  1. Institut für Zellphysiologie der Ruhr-Universität Bochum, Postfach 2148, D-4630, Bochum, Deutschland

    T. Schumacher

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Schumacher, T. Zum Mechanismus der ökonomischen Halteleistung eines glatten Muskels (Byssus retractor anterior,Mytilus edulis). Pflugers Arch. 331, 77–89 (1972). https://doi.org/10.1007/BF00587193

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  • DOI: https://doi.org/10.1007/BF00587193

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