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Effects of different ionic components on afferent responses of vibrissa receptors

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Summary

Afferent responses in single-fibre and multi-fibre preparations of the n. infraorbitalis leading from mechanosensitive receptors of the cat's vibrissae were investigated by application of different isotonic solutions of ionised calcium, sodium, potassium and magnesium.

Under quasi-stationary as well as under time-variable conditions the doseresponse studies of calcium and potassium revealed a non-linear, depressive action on synchronised impulse patterns as far as the spike rate and the spike phase was concerned. In coincidence with the inhibition of neural activity the impulses were shifted to a higher phase angle and a considerable instability of the trigger time point was observed. Contrarily, sodium had an activating effect on the discharge combined with higher spike rates, lower phase angles and a stabilising influence on the synchronisation of afferent impulse patterns. After injection of magnesium no significant modification was found.

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References

  • Andres, K. H.: Über die Feinstruktur der Receptoren an Sinushaaren. Z. Zellforsch.75, 339–365 (1966)

    Google Scholar 

  • Brink, F.: The role of calcium ions in neural processes. Pharmacol. Rev.6, 243–298 (1954)

    Google Scholar 

  • Feng, T. P.: Reversible inexcitability of tactile endings in skin injury. J. Physiol. (Lond.)79, 103–108 (1933)

    Google Scholar 

  • Fitzgerald, O.: Discharges from the sensory organs of the cat's vibrissae and the modification in their activity by ions. J. Physiol. (Lond.)98, 163–178 (1940)

    Google Scholar 

  • Gruber, U. F., Allgöwer, M.: Wasser- und Elektrolythaushalt. In: J. R. Geigy A. G. (Ed.): Documenta Geigy, Wissenschaftliche Tabellen, 7. ed. Basel: Geigy 1968

    Google Scholar 

  • Hahn, J. F.: Stimulus-response relationships in first-order sensory fibres from cat vibrissae. J. Physiol. (Lond.)213, 215–226 (1971)

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: Movement of sodium and potassium ions during nervous activity. Cold Spr. Harb. Symp. quant. Biol.17, 43–52 (1952a)

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. J. Physiol. (Lond.)116, 449–472 (1952b)

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: The components of membrane conductance in the giant axon of Loligo. J. Physiol. (Lond.)116, 473–496 (1952c)

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: The dual effect of membrane potential on sodium conductance in the giant axon of Loligo. J. Physiol. (Lond.)116, 497–506 (1952d)

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. (Lond.)117, 500–544 (1952e)

    Google Scholar 

  • Keidel, W. D.: Electrophysiology of vibratory preception. In: W. D. Neff (Ed.): Contributions to sensory physiology, Vol. III, New York-London: Academic Press 1968

    Google Scholar 

  • Keidel, W. D., Keidel, U. O., Kiang, N. Y. S.: Cortical and peripheral responses to vibratory stimulation of the cat's whiskers. Mass. Inst. Technol. Res. Lab. Electron. quart. Progr. Rept.46, 135–139 (1957)

    Google Scholar 

  • Keidel, W. D., Keidel, U. O., Kiang, N. Y. S.: Peripheral and cortical responses to mechanical stimulation of the cat's vibrissae. Arch. int. Physiol. Biochem.68, 241–262 (1960)

    Google Scholar 

  • Matthews, B. H. C.: The response of a single end organ. J. Physiol. (Lond.)71, 64–110 (1931)

    Google Scholar 

  • Nier, K.: Transformationscharakteristik von Vibrissenreceptoren bei sinusförmiger Reiz-Zeitfunktion. Inaug.-Diss., Marburg 1970

  • Nier, K.: Stabilisation phenomena in synchronous neural activity of vibrissa receptors. Marburg 1971 (im Druck)

  • Nier, K.: Phasenfrequenzgang neuraler Impulsmuster von Vibrissenreceptoren. Pflügers Arch.334, 357–366 (1972)

    Google Scholar 

  • Nier, K., Hensel, H.: Reizsynchronisation afferenter Entladungen von Vibrissenreceptoren. Proceed. I. Europ. Biophysics Congr., Vol. V, pp. 139–143, Baden 1971

    Google Scholar 

  • Nier, K., Hensel, H.: Effects of calcium on afferent responses of the ampullae of Lorenzini. Pflügers Arch.338, 281–287 (1973)

    Google Scholar 

  • Nilsson, B. Y.: Structure and function of the tactile hair receptors on the cat's foreleg. Acta physiol. scand.77, 396–416 (1969)

    Google Scholar 

  • Smith, K. R., Creech, B. J.: Effects of pharmacological agents on the physiological responses of hair discs. Exp. Neurol.19, 477–482 (1967)

    Google Scholar 

  • Talaat, M.: The effect of ions on the cutaneous sensory endings of the frog. J. Physiol. (Lond.)79, 500–507 (1933)

    Google Scholar 

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Authors and Affiliations

  1. Institut für Physiologie, Universität Marburg a. d. Lahn, Deutschhausstr. 2, D-3550, Marburg a. d. Lahn, Germany

    K. Nier

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  1. K. Nier
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This investigation was supported by grant from the Deutsche Forschungsgemeinschaft

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Nier, K. Effects of different ionic components on afferent responses of vibrissa receptors. Pflugers Arch. 347, 27–38 (1974). https://doi.org/10.1007/BF00587052

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  • DOI: https://doi.org/10.1007/BF00587052

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