Skip to main content
SpringerLink
Log in

Optical trapping and manipulation of microscopic particles and biological cells by laser beams

  • Papers
  • Published:
Optical and Quantum Electronics Aims and scope Submit manuscript

Abstract

Optical trapping incorporating visible and near-IR laser beams has become an important tool for precise, noncontact manipulation of various micrometre-sized particles. This paper reviews basic principles and features of single-beam optical trapping of microscopic particles such as biological cells, polystyrene latex spheres, small crystals and metal particles. Trapping forces measured and calculated on the basis of ray optics are discussed. Some interesting applications are also described, including an optical micromotor, all-optical biological cell fusion, observation of nonlinear optical phenomena and microlaser oscillation, and metal particle trapping.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. ASHKIN, J. M. DZIEDZIC, J. E. BJORKHOLM and S. CHU,Opt. Lett. 11 (1986) 288.

    Google Scholar 

  2. S. SATO, Y. HARADA and Y. WASEDA,Opt. Lett. 19 (1994) 1807.

    Google Scholar 

  3. K. SVOBODA and S. M. BLOCK,Opt. Lett. 19 (1994) 930.

    Google Scholar 

  4. S. SATO, M. OHYUMI, H. SHIBATA, H. INABA and Y. OGAWA,Opt. Lett. 16 (1991) 282.

    Google Scholar 

  5. K. SASAKI, M. KOSHIOKA, H. MISAWA, N. KITAMURA and H. MASUHARA,Jpn. J. Appl. Phys. 30 (1991) L907.

  6. A. ASHKIN and J. M. DZIEDZIC,Science 235 (1987) 1517.

    Google Scholar 

  7. A. ASHKIN, J. M. DZIEDZIC and T. YAMANE,Nature 330 (1987) 769.

    Google Scholar 

  8. M. W. BERNS, J. R. AIST, W. H. WRIGHT and H. LIANG,Exp. Cell Res. 198 (1992) 375.

    Google Scholar 

  9. R. S. AFZAL and E. B. TREACY,Rev. Sci. Instrum. 63 (1992) 2157.

    Google Scholar 

  10. F. KUSANO, S. SATO, Y. OGAWA and H. INABA,Med. Biol. Eng. Comput. 29 (supplement, part 2) (1991) 1252.

    Google Scholar 

  11. A. ASHKIN,Biophys. J. 61 (1992) 569.

    Google Scholar 

  12. K. VISSCHER and G. J. BRACKENHOF,Optik 90 (1992) 57.

    Google Scholar 

  13. W. H. WRIGHT, G. J. SONEK and M. W. BERNS,Appl. Opt. 33 (1994) 1735.

    Google Scholar 

  14. W. H. WRIGHT, G. J. SONEK, Y. TADIR and M. W. BERNS,IEEE J. Quantum Electron.26 (1990) 2148.

    Google Scholar 

  15. T. C. BAKKER SCHUT, G. HESSELINK, B. G.DE GROOTH and J. GREVE,Cytometry 12 (1991) 479.

    Google Scholar 

  16. R. GUSSGARD, T. LINDMO and I. BREVIK,J. Opt. Soc. Am. B 9 (1992) 1992.

    Google Scholar 

  17. S. SATO, M. ISHIGURE and H. INABA,Electron. Lett. 27 (1991) 1831.

    Google Scholar 

  18. C. D'HELON, C. W. DEARDEN, H. RUBINSZTEIN-DUNLOP and N. R. HECKENBERG,J. Mod. Opt. 41 (1994) 595.

    Google Scholar 

  19. S. SATO and H. INABA,Opt. Lett. 19 (1994) 927.

    Google Scholar 

  20. E. HIGURASHI, H. UKITA, H. TANAKA and O. OHGUCHI,Appl. Phys. Lett. 64 (1994) 2209.

    Google Scholar 

  21. K. O. GREULICHM, S. MONAJEMBASHI, S. SEEGER and J. WOLFRUM,Cytometry (supplement 4) (1990) 18.

  22. S. SATO, E. HIGURASHI, Y. TAGUCHI and H. INABA,Appl. Phys. B 54 (1992) 531.

    Google Scholar 

  23. S. SATO and H. INABA,Electron. Lett. 28 (1992) 286.

    Google Scholar 

  24. L. MALMQVIST and H. M. HERTZ,Opt. Commun. 94 (1992) 19.

    Google Scholar 

  25. L. MALMQVIST and H. M. HERTZ,Opt. Lett. 19 (1994) 853.

    Google Scholar 

  26. K. SASAKI, M. MISAWA, R. FUJISAWA, N. KITAMURA and H. MASUHARA,Jpn. J. Appl. Phys. 32 (1993) L114.

  27. K. KAMADA, K. SASAKI, H. MISAWA, N. KITAMURA and H. MASUHARA,Chem. Phys. Lett. 210 (1993) 89.

    Google Scholar 

  28. H. MISAWA, R. FUJISAWA, K. SASAKI, N. KITAMURA and H. MASUHARA,Jpn. J. Appl. Phys. 32 (1993) L788.

  29. K. SASAKI, M. KOSHIOKA, H. MISAWA, N. KITAMURA and H. MASUHARA,Appl. Phys. Lett. 60 (1992) 807.

    Google Scholar 

  30. S. M. BLOCK, D. F. BLAIR and H. C. BREG,Nature 338 (1989) 514.

    Google Scholar 

  31. A. ASHKIN, K. SCHUTZE, J. M. DZIEDZIC, U. EUTENEUER and M. SCHLIWA,Nature 348 (1990) 346.

    Google Scholar 

  32. S. M. BLOCK, L. S. B. GOLDSTEIN and B. J. SCHNAPP,Nature 348 (1990) 348.

    Google Scholar 

  33. A. SIMON and A. LIBCHABER,Phys. Rev. Lett. 68 (1992) 3375.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for Advanced Materials Processing, Tohoku University, Katahira 2-1-1, Aoba-ku, 980-77, Sendai, Japan

    S. Sato

  2. Department of Electronics, Tohoku Institute of Technology, 35-1 Yagiyama-kasumicho, Taihaku-ku, 982, Sendai, Japan

    H. Inaba

Authors
  1. S. Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Inaba
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sato, S., Inaba, H. Optical trapping and manipulation of microscopic particles and biological cells by laser beams. Opt Quant Electron 28, 1–16 (1996). https://doi.org/10.1007/BF00578546

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00578546

Keywords

Search

Navigation