Skip to main content
SpringerLink
Log in

Toxicity of iodides and nitrates of mercury for the mouse and rat

  • Published:
Archiv für Toxikologie Aims and scope Submit manuscript

Summary

The toxicity (LD50) of mercurous and mercuric iodide and nitrate for mice and rats has been calculated by Behrens' method after a single dose and an observation time of 6 days. There was no essential difference between the toxicity of corresponding mercurous and mercuric nitrate after parenteral administration but mercurous iodide was less toxic than mercuric iodide after oral administration. The toxicity of parenterally administered mercuric and mercurous iodide was about 1/10 of the toxicity of the corresponding nitrates.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Behrens, B.: Zur Auswertung der Digitalisblätter im Froschversuch. Naunyn-Schmiedebergs Arch. exp. Path. Pharmak.140, 237–256 (1929).

    Google Scholar 

  • Grawitz, E. R., u.A. Waegner: Zur Statistik und Klinik der Vergiftungen an der Hand von 1838 Fällen. Z. klin. Med.106, 783–792 (1927).

    Google Scholar 

  • Handbook of chemistry and physics, 43rd edit., S. 1698. Cleveland: Chemical Ruber Publ. Co. 1961.

  • Hietanen, S., andL. G. Sillén: On the standard potentials of mercury, and the equilibrium Hg2+ + Hg(1) ⇌ Hg +22 in nitrate and perchlorate solutions. Ark. Kemi (Stockh.)10, 103–125 (1956).

    Google Scholar 

  • Lehman, A. J.: Chemicals in foods: A report to the association of food and drug officials on current developments. Part II. Pesticides. Quart. Bull. of the Association of Food & Drug Officials of the United States15, 122–133 (1951).

    Google Scholar 

  • Lehman, R. A., E. E. King andH. Taube: The pharmacology of thiomerin. J. Pharmacol. exp. Ther.99, 149–162 (1950).

    Google Scholar 

  • Ljungdahl, M.: (1)Rezepthandbuch auf Grund der Arzneibücher der nordischen Länder, S. 282. Malmö: Gleerups 1952.

    Google Scholar 

  • —: (2)Rezeptbuch auf Grund der Arzneibücher der nordischen Länder, S. 279. The Merck Index of Chemicals and Drugs, 7th edit., S. 651. Rahway: Merck & Co. Inc. 1960.

    Google Scholar 

  • Moeschlin, S.: Klinik und Therapie der Vergiftungen, 3. Aufl., S. 75. Stuttgart: Georg Thieme 1959.

    Google Scholar 

  • Osol, A., andG. E. Farrar: The dispensatory of the United States of America, 25th edit., S. 810. Philadelphia and Montreal: Lippincott 1955.

    Google Scholar 

  • Sollman, T.: A manual of Pharmacology, 8th edit., S. 1317. Philadelphia and London: W. B. Saunders Co. 1957.

    Google Scholar 

  • Swensson, Å.: Investigations on the toxicity of some organic mercury compounds which are used as seed disinfectants. Acta med. scand.143, fasc. V, 365–384 (1952).

    Google Scholar 

  • Ulfvarsson, U.: Personal communication.

Download references

Author information

Authors and Affiliations

  1. Department of Occupational Medicine, Karolinska sjukhuset, Stockholm

    C. -J. Göthe & L. Sundell

  2. King Gustaf V Research Institute, Stockholm

    C. -J. Göthe & L. Sundell

Authors
  1. C. -J. Göthe
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Sundell
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Göthe, C.J., Sundell, L. Toxicity of iodides and nitrates of mercury for the mouse and rat. Arch. Toxikol. 20, 226–229 (1964). https://doi.org/10.1007/BF00577895

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00577895

Keywords

Search

Navigation