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Distamycin A-DAPI banding of nonfluorescent Y (Ynf) chromosomes in 45,X/46,XYnf mosaicism

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Summary

The distamycin A-DAPI banding patterns of nonfluorescent, nonheterochromatic Y chromosomes (Ynf) in two patients with 45,X/46,XYnf mosaicism were investigated. In both cases moderately fluorescent bands were observed near the centromere and on the distal long arm of the Ynf. These bands were similar to the centrometric band on normal Y chromosomes and support the hypothesis that the Ynf is an isodicentric chromosome derived from the proximal portion of the Y chromosome.

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Wisniewski, L.P., Hirschhorn, K. Distamycin A-DAPI banding of nonfluorescent Y (Ynf) chromosomes in 45,X/46,XYnf mosaicism. Hum Genet 60, 130–132 (1982). https://doi.org/10.1007/BF00569698

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  • DOI: https://doi.org/10.1007/BF00569698

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