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The structure of fetidine

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Summary

Fetidine is a binary aporphine-benzyltetrahydroisoquinoline alkaloid. A structural formula for fetidine has been proposed on the basis of the isolation of (+)-laudanosine (IIIa) and (+)-isoboldine (IV) from the degradation of fetidine (I) with sodium in liquid ammonia.

The obtaining of (+)-laudanosine and (+)-glaucine has established the absolute configuration of the two asymmetric centers of fetidine.

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Authors and Affiliations

  1. Institute of the Chemistry of Plant Substances, AS UzSSR, USSR

    Z. F. Ismailov & S. Yu. Yunusov

Authors
  1. Z. F. Ismailov
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  2. S. Yu. Yunusov
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Additional information

Khimiya Prirodnykh Soedinenii, Vol. 2, No. 1, pp. 43–48, 1966

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Ismailov, Z.F., Yunusov, S.Y. The structure of fetidine. Chem Nat Compd 2, 35–39 (1966). https://doi.org/10.1007/BF00566598

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  • DOI: https://doi.org/10.1007/BF00566598

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