Summary
α,ω-Bisquaternary salts of the pyrrolizidine series have been synthesized by the reaction of α,ω-dibromoalkanes with some products of the cleavage of pyrrolizidine alkaloids (lindelofidine, hydroxyheliotridene, and their esters).
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Literature cited
D. A. Kharkevich, The Pharmacology of Curaremimetic Agents [in Russian], Moscow (1969).
A. S. Labenskii and G. P. Men'shikov, Zh. Obshch. Khim.,18, 1836 (1948).
G. P. Men'shikov, Ber.,68, 1051 (1935).
Additional information
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 77–80, January–February, 1977.
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Shakhidoyatov, K.M., Abdullaev, N.P. & Kadyrov, C.S. Bisquaternary salts of pyrrolizidine alkaloids and their derivatives. Chem Nat Compd 13, 65–68 (1977). https://doi.org/10.1007/BF00566173
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DOI: https://doi.org/10.1007/BF00566173