Summary
It has been found by chromato-mass spectrometry that the main product of the transformation of deoxy-vasicinone excreted with rat urine in the unbound form is vasicinone. Vasicinone used as a drug is excreted predominantly in the unchanged form.
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Additional information
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 250–254, March–April, 1977.
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Plugar', V.N., Gorovits, T.T., Tulyaganov, N. et al. Transformations of alkaloids of the quinazolin-4-one group in the animal organism. Chem Nat Compd 13, 213–216 (1977). https://doi.org/10.1007/BF00563951
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DOI: https://doi.org/10.1007/BF00563951