Conclusions
1. The PÉFAG-1 apparatus and its portable small-scale version can be used not only to detect hepatitis B antigen, but also to detect antigens of tick-borne encephalitis and meningococcal infection and other bacterial and viral antigens for the diagnosis of infectious diseases.
2. The sensitivity of determination of antigens and antibodies on the PÉFAG-1 apparatus was found to be 2–3 times higher than radial immunodiffusion and 10–20 times higher than countercurrent immunodiffusion.
3. When the PÉFAG-1 apparatus is used to diagnose virus hepatitis results can be obtained in 30–45 min, compared with 10–15 min for the modified instrument.
4. The apparatus guarantees high specificity, demonstrability, and reproducibility of the results.
Similar content being viewed by others
Literature cited
A. D. Aleksandrov, N. G. Anufrieva, T. I. Zhmyrina, and A. F. Moroz, Zh. Mikrobiol., No. 1, 14 (1984).
A. A. Babaev, L. P. Mel'nikova, and Z. L. Dzhabarova, Vopr. Virusol., No. 5, 577 (1983).
V. A. Burlev and V. I. Sobolev, Collection of Papers by Inventors and Efficiency Experts [in Russian], Moscow (1984), p. 24.
I. P. Gontar', S. M. Farber, V. I. Efremenko, et al., Zh. Mikrobiol., No. 3, 55 (1984).
L. B. Kozlov, S. G. Kostylev, and A. D. Evtushenko, Vopr. Virusol., No. 5, 571 (1983).
N. N. Piven' and V. I. Ilyukhin, Zh. Mikrobiol., No. 4, 78 (1981).
V. I. Sobolev, A. V. Bashtanov, N. K. Akkuratova, et al., Investigation of Optimal Principles of Design of Electrophoretic Instruments for Immunologic Investigations. Research Report, [in Russian], Leningrad (1982).
V. I. Sobolev, A. V. Bashtanov, V. A. Burlev, et al., Medical Engineering News [in Russian], Moscow (1980), p. 24.
B. L. Cherkasskii, A. G. Knop, and V. Yu. Markov, Zh. Mikrobiol., No. 1, 95 (1984).
G. C. Klein, J. Clin. Microbiol.,11, 27 (1980).
Additional information
All-Union Research and Design Institute for Medical Laboratory Equipment, Leningrad. Translated from Meditsinskaya Tekhnika, No. 5, pp. 44–46, September–October, 1986.
Rights and permissions
About this article
Cite this article
Sobolev, V.I., Bashtanov, A.V., Burlev, V.A. et al. The use of immunoelectrophoretic apparatus for rapid diagnosis. Biomed Eng 20, 179–181 (1986). https://doi.org/10.1007/BF00563387
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00563387