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Zur ultrastruktur und sauren phosphatase-aktivität in den schweißdrüsen mit “clear, reticulated cytoplasm”

The ultrastructure and acid phosphatase activity in the sweat glands with “clear, reticulated cytoplasm”

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Summary

Investigations were carried out on the ultrastructure and distribution of acid phosphatase in the human sweat glands with “clear, reticulated cytoplasm”. It is probable that the gland cells with vacuolized cytoplasm develop from the serous gland cells through a morphologically recognizable intermediate state.

An extralysosomal activity of acid phosphatase occurs in the vacuolized gland cells. The free distribution of the enzyme activity is focal. A correlation between these findings and a possible holocrine mode of secretion is discussed.

Zusammenfassung

Die Ultrastruktur und die Verteilung der sauren Phosphatase wurden in den menschlichen Schweißdrüsen mit “clear, reticulated cytoplasm” untersucht. Die Drüsenzellen mit vakuolisiertem Cytoplasma entwickeln sich wahrscheinlich über eine morphologisch faßbare Zwischenstufe aus den serösen Drüsenzellen.

Die saure Phosphatase-Aktivitäten kommen in den vakuolisierten Zellen auch extralysosomal vor, wobei die Verteilung der Enzymaktivität anzeigenden Präzipitate fokal erfolgt. Diese Befunde wurden im Zusammenhang mit einem möglichen holokrinen Sekretionsmodus diskutiert.

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Literatur

  • Belcher, R. W.: Ultrastructure and function of eccrine glands in the mucopolysaccharidoses. Arch. Path.96, 339 (1973)

    Google Scholar 

  • Bowen, I. D., Davies, P.: The fine structural distribution of acid phosphatase in the digestive gland of arion hortensis (Fer.). Protoplasma73, 73–81 (1971)

    Google Scholar 

  • Brandes, D.: Observation on the apparent mode of formation of “pure” lysosomes. J. Ultrastruct. Res.12, 63–80 (1965)

    Google Scholar 

  • Breathnach, A. S.: An atlas of the ultrastructure of human skin development, differentiation and post-natal features. London: J. & A. Churchill 1971

    Google Scholar 

  • Braun-Falco, O., Rupec, M.: Die Verteilung der sauren Phosphatase bei normaler und psoriatischer Verhornung (Eine elektronenmikroskopisch-cytochemische Untersuchung). Dermatologica (Basel)134, 225–242 (1967)

    Google Scholar 

  • Braun-Falco, O., Rupec, M.: Apokrine Schweißdrüsen. In: Jadassohn, J., Hdb. Haut-Geschl.-Krkh. Ergänzungswerk I/1, S. 267. Berlin-Heidelberg-New York: Springer 1968

    Google Scholar 

  • Cormia, F. E., Kuykendall, V.: Cytochemical studies of eccrine sweat tubules: cellular differentiation and glycogen content. J. invest. Derm.24, 527–535 (1955)

    Google Scholar 

  • Daemes, W. Th., Wisse, E., Brederoo, P.: Electron microscopy of the vacuolar apparatus. In: Lysosomes in biology and pathology 1, S. 64–112. Amsterdam-London: North-Holland Publishing Comp. 1969

    Google Scholar 

  • Ellis, R. A.: Eccrine sweat glands: Electron microscopy, cytochemistry and anatomy. In: Jadassohn, J., Hdb. Haut-Geschl.-Krkh. Ergänzungswerk I/1, S. 224. Berlin-Heidelberg-New York: Springer 1968

    Google Scholar 

  • Hibbs, R. G.: The fine structure of human eccrine sweat glands. Amer. J. Anat.103, 201 (1958)

    Google Scholar 

  • Holyoke, J. B., Lobitz Jr., W. C.: Histologic variations in the structure of human eccrine sweat glands. J. invest. Derm.18, 147–167 (1952)

    Google Scholar 

  • Lazarus, S., Volk, B. W.: Ultrastructure and acid phosphate distribution in the pancreas of rabbits. Arch. Path.80, 135–147 (1965)

    Google Scholar 

  • Lloyd, J. B., Beck, F.: Lysosomes. In: The cell in medical science, Vol. 1, S. 273. London-New York: Academic Press 1974

    Google Scholar 

  • Lockshin, R. A., Williams, C. M.: Programmed cell death — I. Cytology of degeneration in the intersegmental muscles of the Pernyi Silkmoth. J. Ins. Physiol.11, 123–133 (1965)

    Google Scholar 

  • Montagna, W.: The structure and function of skin. New York-London: Academic Press 1962

    Google Scholar 

  • Montagna, W., Parakkal, P. F.: The structure and function of skin. New York-London: Academic Press 1974

    Google Scholar 

  • Rupec, M.: Zur Ultrastruktur atypisch aussebender Zellen in normalen menschlichen apokrinen Schweißdrüsen. Arch. klin. exp. Derm.228, 452–458 (1967)

    Google Scholar 

  • Rupec, M.: Die Lysosomen. Z. Haut- u. Geschl.-Kr.45, 67–83 (1970)

    Google Scholar 

  • Rupec, M.: O problemu lipofuscinskih granula u žljezdanim stanicama znojnica. Acta derm. Iug. (im Druck)

  • Rupec, M., Braun-Falco, O.: Zur Frage lysosomaler Aktivität in normalen menschlichen Talgdrüsen. Arch. klin. exp. Derm.232, 312–324 (1968)

    Google Scholar 

  • Schaumburg-Lever, G., Lever, W. F.: Secretion from human apocrine glands: an electron microscopic study. J. invest. Derm.64, 38–41 (1975)

    Google Scholar 

  • Schin, K. S., Clever, E.: Lysosomal and free acid phosphatase in salivary glands of chironomus tentans. Science150, 1053–1055 (1965)

    Google Scholar 

  • Terzakis, J. A.: The ultrastructure of monkey eccrine sweat glands. Z. Zellforsch.64, 493–509 (1964)

    Google Scholar 

  • Tsuji, T., Yamamoto, T.: Acquired generalized anhidrosis. Arch. Derm.112, 1310–1314 (1976)

    Google Scholar 

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Authors and Affiliations

  1. Univ.-Hautklinik, Deutschhausstr. 9, D-3550, Marburg/Lahn, Germany

    M. Rupec

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  1. M. Rupec
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Mit freundlicher Unterstützung durch die Deutsche Forschungsgemeinschaft

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Rupec, M. Zur ultrastruktur und sauren phosphatase-aktivität in den schweißdrüsen mit “clear, reticulated cytoplasm”. Arch. Derm. Res. 258, 193–201 (1977). https://doi.org/10.1007/BF00561625

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  • DOI: https://doi.org/10.1007/BF00561625

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