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The effect of temperature on biochemical and molecular properties ofDrosophila alcohol dehydrogenase

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Abstract

The gene products of the two major alleles of alcohol dehydrogenase (ADH-F and ADH-S) have been subjected to kinetic and biochemical analyses over a range of temperatures. Although temperature was found to have a significant effect on both kinetic and biochemical properties ofDrosophila ADH, no significant differential effect was observed between the major ADH allozymes. The results are discussed within the context of the selective maintenance ofAdh polymorphism in natural populations.

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Authors and Affiliations

  1. Department of Genetics, University of Georgia, 30602, Athens, Georgia

    Kevin C. McElfresh & John F. McDonald

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  1. Kevin C. McElfresh
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  2. John F. McDonald
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Additional information

A significant portion of the calculations was made possible by a grant from DECOR (1982) which provided a PDP-11/34 minicomputer to the Department of Genetics, University of Georgia. This work was supported by NSF Grant DEB-82-00965 to J.M.

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McElfresh, K.C., McDonald, J.F. The effect of temperature on biochemical and molecular properties ofDrosophila alcohol dehydrogenase. Biochem Genet 24, 873–889 (1986). https://doi.org/10.1007/BF00554526

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  • DOI: https://doi.org/10.1007/BF00554526

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