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Etheno derivatives of adenine and cytosine (review)

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The method of modification of heterocyclic bases of nucleic acids with chloroacetaldehyde and other α-halo carbonyl compounds is examined in this review. The mechanism, kinetics, and scope of the reaction, the chemical properties of modified derivatives of adenine and cytosine, and the possibilities of the application of etheno derivatives of adenine and cytosine in biochemistry and molecular biology are discussed.

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Authors and Affiliations

  1. M. M. Shemyakin Institute of Bioorganic Chemistry, Academy of Sciences of the USSR, 117312, Moscow

    A. A. Kost & M. V. Ivanov

  2. M. V. Lomonosov Moscow State University, 117234, Moscow

    A. A. Kost & M. V. Ivanov

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  1. A. A. Kost
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  2. M. V. Ivanov
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 291–305, March, 1980.

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Kost, A.A., Ivanov, M.V. Etheno derivatives of adenine and cytosine (review). Chem Heterocycl Compd 16, 209–221 (1980). https://doi.org/10.1007/BF00553878

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