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Inclusion complexes of prochiral heterocyclic ketones with β-cyclodextrins and their reduction with sodium borohydride

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Alkyl(2-furyl), alkyl(2-thienyl), and methyl pyridyl ketones form stoichiometric inclusion complexes with β-cyclodextrins. Reduction of these complexes in aqueous solution of Na2CO3 at room temperature yields the corresponding secondary alcohols with an optical yield which attains 27%.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, LV-1006, Riga

    Yu. Gol'dberg, E. Abele, K. Rubina, Yu. Popelis & M. Shimanska

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  1. Yu. Gol'dberg
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  2. E. Abele
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  3. K. Rubina
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  4. Yu. Popelis
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  5. M. Shimanska
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1621–1627, December, 1993.

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Gol'dberg, Y., Abele, E., Rubina, K. et al. Inclusion complexes of prochiral heterocyclic ketones with β-cyclodextrins and their reduction with sodium borohydride. Chem Heterocycl Compd 29, 1399–1404 (1993). https://doi.org/10.1007/BF00531399

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  • DOI: https://doi.org/10.1007/BF00531399

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