Summary
The induction of cytochrome P-450 in Candida guilliermondii by different growth substrates was investigated. Hexadecane is a strong inducer, whereas its oxidation products induce only weakly. It could be shown that the oxygen concentration in the medium influences the cytochrome P-450 content in cells growing on hexadecane. At oxygen concentrations between 100% and 15% of saturation the cytochrome P-450 content reaches 25–35 nmol/g dry weight. Reducing the oxygen to lower concentrations increase the cytochrome P-450 content up to approximately 100 nmol/g dry weight.
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Mauersberger, S., Matyashova, R.N., Müller, HG. et al. Influence of the growth substrate and the oxygen concentration in the medium on the cytochrome P-450 content in Candida guilliermondii . European J. Appl. Microbiol. Biotechnol. 9, 285–294 (1980). https://doi.org/10.1007/BF00508105
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DOI: https://doi.org/10.1007/BF00508105