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Utilization of a benzyl protective group in the synthesis of tetrahydroisoquinoline derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding N-benzyl-1,2,3,4-tetrahydroisoquinolines, the debenzylation of which is realized by hydrogenation in the presence of Pd black, were synthesized by the reaction of 1-(3-hydroxyphenyl)-2-benzylaminoethanol with aldehydes.

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Literature cited

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Authors and Affiliations

  1. Institute of Biophysics, Ministry of Public Health of the USSR, 123182, Moscow

    T. V. Alpatova & V. G. Yashunskii

Authors
  1. T. V. Alpatova
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  2. V. G. Yashunskii
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1084–1087, August, 1981.

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Alpatova, T.V., Yashunskii, V.G. Utilization of a benzyl protective group in the synthesis of tetrahydroisoquinoline derivatives. Chem Heterocycl Compd 17, 804–807 (1981). https://doi.org/10.1007/BF00503663

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  • DOI: https://doi.org/10.1007/BF00503663

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