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Avoidance acquisition and CNS stimulants

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Summary

Using avoidance behavior in a Skinner box, acquisition was measured in naive rats after the administration of various CNS stimulants. Discrimination between two bars (response on one avoided the shock, the other was ineffective) and the discrimination between avoidance response and intertrial response were measured by comparing response ratios. A change in these ratios indicated a change in the acquisition because a non-specific and overal increase of all responding after a CNS stimulant would not change these ratios from that of controls.

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Authors and Affiliations

  1. Department of Pharmacology, Human Health Research and Development Laboratories, The Dow Chemical Company, Zionsville, Indiana

    A. S. Kulkarni

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  1. A. S. Kulkarni
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Kulkarni, A.S. Avoidance acquisition and CNS stimulants. Naunyn-Schmiedeberg's Arch. Pharmacol. 273, 394–400 (1972). https://doi.org/10.1007/BF00499673

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  • DOI: https://doi.org/10.1007/BF00499673

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