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Identification of the Pm and PmS human parotid salivary proteins as basic proline-rich proteins

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Abstract

Amino acid composition and electrophoretic mobility suggest that two polymorphic proteins in human parotid saliva, Pm and PmS, are basic proline-rich proteins. Comparison of two basic proline-rich proteins previously isolated by D. L. Kauffman and P. J. Keller (1979) [Arch. Oral. Biol. 24: 249], IB-6 and IB-9, with PmS and Pm demonstrated corresponding electrophoretic mobilities on cationic polyacrylamide slab gels. Further, the amino acid compositions of IB-9 and Pm were found to be similar. Although differences in amino acid composition and carbohydrate content were noted, such differences could be accounted for, suggesting that IB-9 and Pm are identical.

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This work was supported by Research Grants DE 05252 and DE 02600 from the National Institute of Dental Research.

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Anderson, L.C., Kauffman, D.L. & Keller, P.J. Identification of the Pm and PmS human parotid salivary proteins as basic proline-rich proteins. Biochem Genet 20, 1131–1137 (1982). https://doi.org/10.1007/BF00498937

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  • DOI: https://doi.org/10.1007/BF00498937

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