Abstract
The effect of ECT on concentrations of monoamine metabolites in lumbar CSF of psychotic women with a schizophrenic symptomatology was examined. After a series of ECT there was a significant reduction of the concentration of the major noradrenaline metabolite, MOPEG. Levels of HVA, 5-HIAA, prolactin, or total protein in CSF were not significantly influenced by treatment. The results indicate a specific alteration of central noradrenaline metabolism in relation to ECT.
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Härnryd, C., Bjerkenstedt, L., Grimm, V.E. et al. Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment. Psychopharmacology 64, 131–134 (1979). https://doi.org/10.1007/BF00496052
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DOI: https://doi.org/10.1007/BF00496052