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A comparison of aspergillus fumigatus antigens by counterimmunoelectrophoresis

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Abstract

Counterimmunoelectrophoresis (CIE) has been evaluated for routine diagnostic work, using antigens prepared from 2 different isolates of Aspergillus fumigatus, at 2 different concentrations. Additional antigens prepared in a variety of ways and 2 commercially available antigens (Bencard, London; Institut Pasteur, Paris, France) have been compared with the routine antigens. It has been shown that the use of the routine antigens will detect the majority of positive reactions. At optimal reacting concentrations antibodies were detected in 75% of asthmatic patients. In sera from patients with a presumptive diagnosis of allergic aspergillosis, CIE will detect twice as many positive reactions as a conventional agar gel diffusion test.

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References

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Authors and Affiliations

  1. Mycological Reference Laboratory, of the Public Health Laboratory Service, London School of Hygiene & Tropical Medicine, Keppel Street, WC1E 7HT, London

    Christine M. Philpot & D. W. R. Mackenzie

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  1. Christine M. Philpot
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  2. D. W. R. Mackenzie
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Philpot, C.M., Mackenzie, D.W.R. A comparison of aspergillus fumigatus antigens by counterimmunoelectrophoresis. Mycopathologia 58, 19–20 (1976). https://doi.org/10.1007/BF00493588

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  • DOI: https://doi.org/10.1007/BF00493588

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