Summary
Carbonic anhydrase (CA) activity is demonstrated in lymphoid tissue for the first time using the histochemical (Hansson's) method. A CA-positive reaction was seen in lymphocytes present in T-lymphocyte areas in both the lymph node and the spleen. The most intense staining was seen in the small T-lymphocytes, whereas the mediumsized T-lymphocytes were less markedly stained. The cortical lymphocytes in the thymus were completely devoid of staining, but the small medullary T-lymphocytes stained intensely. The results suggest that peripheral and thymic medullary T-lymphocytes contain CA activity, which appears in these cells during their maturation in the thymus.
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Parkkila, S., Rajaniemi, H. Carbonic anhydrase activity in peripheral T-lymphocytes and appearance of the activity during their maturation in the thymus. Histochemistry 91, 479–482 (1989). https://doi.org/10.1007/BF00492519
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DOI: https://doi.org/10.1007/BF00492519