Abstract
We have synthesized 2-(thienyl-2)imidazole and its N-methyl derivative. The latter product was obtained by nitration, bromination, acylation, and formylation, occurring as a rule on the thiophene ring. A general method for methylating 2-R-imidazoles with methyl iodide KOH-dimethoxy ethane is proposed.
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For Communication 1 see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1414–1418, October, 1991.
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Stoyanov, V.M., El'chaninov, M.M. & Pozharskii, A.F. Investigations of 2-substituted imidazoles. 2. Synthesis and electrophilic substitution of 1-methyl-2-(thienyl-2)imidazole. A convenient method of methylation of 2-R-imidazoles. Chem Heterocycl Compd 27, 1140–1144 (1991). https://doi.org/10.1007/BF00486814
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DOI: https://doi.org/10.1007/BF00486814