Abstract
Reaction of isopropylphenyl- and isopropyl-2-thienylketoximes with acetylene, catalyzed by the system MOH (M=Na, K)-DMSO, gave 2-phenyl- and 2-(2-thienyl)-3,3-dimethyl-3H-pyrroles as well as the reaction intermediates O-vinylisopropylphenylketoxime and 2-phenyl-3,3-dimethyl-5-hydroxypyrroline. The yield of the condensation products depends on the structure of the ketoximes and the conditions for the reaction with acetylene.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1371–1374, October, 1991.
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Korostova, S.E., Shevchenko, S.G. & Sigalov, M.V. A novel synthesis of 3H-pyrroles. Chem Heterocycl Compd 27, 1101–1104 (1991). https://doi.org/10.1007/BF00486806
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DOI: https://doi.org/10.1007/BF00486806