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Serum prealbumin in inbred strains of Mus musculus

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Abstract

Separation of blood serum prealbumin from ten strains of inbred mice was accomplished using acrylamide electrophoresis. Nine of these strains demonstrated the same five prealbumin bands; however, the C57BL/6JWg strain showed a sixth band. The use of appropriate crosses of C57BL/6JWg and DBA/2fWg showed this unique band to be the product of a single autosomal dominant gene. We have named the gene for this prealbumin band Pre-1 and have shown a map distance between Pre-1 and b of 2.25 cM. Only one of the five prealbumins present in all strains of mice tested showed nonspecific esterase activity.

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Authors and Affiliations

  1. Mutagenesis Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina

    Larry Claxton & H. V. Malling

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  1. Larry Claxton
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  2. H. V. Malling
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  3. H. E. Walburg
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Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee (Operated by Union Carbide Corporation for the U.S. Atomic Energy Commission).

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Claxton, L., Malling, H.V. & Walburg, H.E. Serum prealbumin in inbred strains of Mus musculus . Biochem Genet 11, 97–102 (1974). https://doi.org/10.1007/BF00485767

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  • DOI: https://doi.org/10.1007/BF00485767

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