Abstract
A cluster of esterase loci has been identified on a segment of a rat linkage group V; however, the linear order of all the loci has not been established. We estimated the recombination frequencies of two locus combinations among five esterase loci (Es-1, Es-2, Es-3, Es-4, and Es-Si) and the linear order of the loci by using three sets of backcross matings: (1) (K:W × IS) × IS, (2) (K:W × IS) × IS, and (3) (SHR × W) × W). The linear order was determined to be Es-1-Es-4-Es-2-Es-3-Es-Si, although the order of Es-2 and Es-4 remains tentative. The sexinfluenced esterase (Es-Si) was demonstrated to be distinct from Es-1 and was proposed to be Es-Si locus with two alleles of Es-Si a (positive) and Es-Si b (null).
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This work was partly supported by Grants-in-Aid for Scientific Research, No. 339020 (1978), from the Ministry of Education, Science and Culture, Japan.
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Yamada, J., Nikaido, H. & Matsumoto, S. Linkage analyses among five esterase loci in the laboratory rat (Rattus norvegicus). Biochem Genet 18, 433–438 (1980). https://doi.org/10.1007/BF00484392
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DOI: https://doi.org/10.1007/BF00484392