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Total synthesis of 5, 6, 7, 8-tetrahydroquinolines and quinolines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The condensation of 2-ethoxy-2,3-tetramethylene-3,4-dihydro-l,2-pyran with acetal and ethyl orthoformate was studied. The condensation products react with ammonia on γ-aluminum oxide to form the corresponding tetrahydroquinolines; a mixture of tetrahydroquinolines and quinolines is formed from these condensation products on platinized -γ-aluminum oxide.

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Literature Cited

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1533–1534, November, 1971

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Chumakov, Y.I., Bulgakova, N.B. Total synthesis of 5, 6, 7, 8-tetrahydroquinolines and quinolines. Chem Heterocycl Compd 7, 1427–1428 (1971). https://doi.org/10.1007/BF00481111

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  • DOI: https://doi.org/10.1007/BF00481111

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