Abstract
The reaction of cyclohexylidenecyanothioacetamide with N,N-dimethylformamide dimethyl acetal was studied. This transformation, depending on the reaction conditions, leads to different results: when the starting reagents are refluxed without a solvent, 3-(methylsulfanyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile is formed, and refluxing in benzene leads to 2-cyano-3-(dimethylamino)prop-2-enethioamide. The structure of these products was studied by XRD analysts.
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Translated from Zhurnal Organicheskoi Khimii, 2022, Vol. 58, No. 5, pp. 469–475 https://doi.org/10.31857/S0514749222050032.
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Dyachenko, I.V., Dyachenko, V.D., Dorovatovskii, P.V. et al. New Synthesis of Tetrahydroisoquinolines. Russ J Org Chem 58, 657–662 (2022). https://doi.org/10.1134/S1070428022050037
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DOI: https://doi.org/10.1134/S1070428022050037