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Indole chemistry

XXVI. Mercuration of 1-methylindoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1-Methylindoles are smoothly mercurated with substitution of the hydrogen atoms in the 3 position of the pyrrole ring. If, however, the latter is occupied, they are substituted in the 2 position. The resulting 2- or 3-chloromercuriindoles are readily converted to symmetrical diindolylmercury compounds, and the chloromercuri group is replaced by iodine and acyl groups; in the presence of palladium salts, they react with acrylic acid esters to form indolylacrylic acid esters.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, USSR

    L. G. Yudin, A. N. Kost & A. I. Pavlyuchenko

Authors
  1. L. G. Yudin
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  2. A. N. Kost
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  3. A. I. Pavlyuchenko
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Additional information

See [1] for communication XXV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1517–1521, November, 1971.

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Yudin, L.G., Kost, A.N. & Pavlyuchenko, A.I. Indole chemistry. Chem Heterocycl Compd 7, 1411–1415 (1971). https://doi.org/10.1007/BF00481107

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  • DOI: https://doi.org/10.1007/BF00481107

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