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Synthesis and structures of 6-methyl-1-(2-R-phenyl)-dihydropyrimidine-2,4-dione derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

N-Aryl-Β-methyl-Β-alanines were synthesized by the reaction of aromatic amines with crotonic acid. The products were converted to dihydropyrimidine-2,4-dione derivatives. Alkylation, acylotion, and oximation of 1-arylpyrimidine-2,4-diones were carried out. Conformational analysis of the compounds obtained was carried out by dynamic NMR methods.

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Authors and Affiliations

  1. Institute of Organic Synthesis, Latvian Academy of Sciences, 226006, Riga

    R. S. Baltrushis, V. Yu. Mitskyavichyus, I. Ch. Bilinskaite, R. M. Zolotoyabko & É. É. Liepin'sh

Authors
  1. R. S. Baltrushis
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  2. V. Yu. Mitskyavichyus
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  3. I. Ch. Bilinskaite
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  4. R. M. Zolotoyabko
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  5. É. É. Liepin'sh
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1096–1106, August, 1990.

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Baltrushis, R.S., Mitskyavichyus, V.Y., Bilinskaite, I.C. et al. Synthesis and structures of 6-methyl-1-(2-R-phenyl)-dihydropyrimidine-2,4-dione derivatives. Chem Heterocycl Compd 26, 918–927 (1990). https://doi.org/10.1007/BF00480871

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  • DOI: https://doi.org/10.1007/BF00480871

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