Abstract
α-(1-Cytosinyl)-γ-butyrolactone was obtained by condensation of bis(trimethylsilyl)cytosine with α-bromobutyrolactone. The reduction of α-(1-cytosinyl)-γ-butyrolactone with sodium borohydride gave N1-(1,4-dihydroxy-2-butyl)cytosine, the acylation of which with benzoyl chloride and subsequent partial hydrolysis gave N1-(1,4-dihydroxy-2-butyl)-N4-benzoylcytosine.
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S. A. Giller, R. A. Zhuk, A. É. Berzinya, L. T. Kaulinya, and L. A. Sherin', Khim. Geterotsikl. Soedin., 1662 (1974).
S. A. Giller, Z. A. Shomshtein, and T. A. Popova, Khim. Geterotsikl. Soedin., 409 (1975).
G. J. Koomen and U. K. Pandit, J. Chem. Soc., Perkin I, 1929 (1973).
S. A. Giller, R. A. Zhuk, and Ya. G. Nashatyr', Khim. Geterotsikl. Soedin., 557 (1968).
G. V. Venkstern and A. A. Baev, Absorption Spectra of Minor Bases, Their Nucleosides and Nucleotides, and Some Oligonucleotides [in Russian], Moscow (1965), p. 14.
T. Nishimura and I. Iwai, Chem. Pharm. Bull., 12, 357 (1964).
E. Wittenburg, Z. Chem., 4, 303 (1964).
T. T. Sakai, A. L. Pogolotti, and D. V. Santi, J. Heterocycl. Chem., 5, 849 (1968).
H. Plieninger, Ber., 83, 267 (1950).
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See [1] for communication VIII.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 694–698, May, 1975
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Giller, S.A., Zhuk, R.A., Berzinya, A.É. et al. Analogs of pyrimidine nucleosides. Chem Heterocycl Compd 11, 603–606 (1975). https://doi.org/10.1007/BF00480489
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DOI: https://doi.org/10.1007/BF00480489