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Pyridinium salts

I. Reduction of 4-(benzazol-2-yl)pyridinium salts in a neutral medium

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

New 4- (benzazol-2-yl)pyridinium salts have been synthesized. Their reduction in a neutral medium with sodium tetrahydroborate has given 2-(1,2,5,6-tetrahydropyridin-4-yl)benzazoles. The catalytic hydrogenation of the latter leads to piperidine derivatives which have also been synthesized by an independent route.

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Literature cited

  1. D. Bek and K. Schenker, Helv. Chim. Acta. 51, 260 (1968).

    Google Scholar 

  2. R. N. Schut, F. E. Ward, and O. J. Lorenzetti, J. Med. Chem., 13, 395 (1970).

    Google Scholar 

  3. G. E. Wiegand, V. J. Bauer, and S. R. Safir, J. Med. Chem., 12, 943 (1969).

    Google Scholar 

  4. V. J. Bauer, W. J. Fanshave, H. P. Dalalian, and S. R. Safir, J. Med. Chem., 11, 984 (1968).

    Google Scholar 

  5. Miles Lab., Inc., GFR Patent 1,901,637 (1969); Chem. Abstr., 72, 66,828 (1970).

    Google Scholar 

  6. K. Hideg and O. H. Hankovszky. Acta Chim. Acad. Sci. Hung., 43, 263 (1963).

    Google Scholar 

  7. V. M. Zubarovskii and A. I. Voronina, Zh. Obshch. Khim., 23, 1561 (1953).

    Google Scholar 

  8. J. W. Verhoeven, I. P. Dirx, and T. J. Deboer, Tetrahedron, 25, 4037 (1969).

    Google Scholar 

  9. R. P. Barnes, J. H. Graham, and M. D. Taylor, J. Org. Chem., 23, 1561 (1958).

    Google Scholar 

  10. M. Ferles, Coll., 24, 2221 (1959).

    Google Scholar 

  11. R. E. Lyle, E. W. Southwick, and J. J. Kaminsky, J. Amer. Chem. Soc., 94, 1413 (1972).

    Google Scholar 

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 104–107, January, 1974.

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Zarin', P.P., Lavrinovich, É.S. & Aren, A.K. Pyridinium salts. Chem Heterocycl Compd 10, 92–95 (1974). https://doi.org/10.1007/BF00475918

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  • DOI: https://doi.org/10.1007/BF00475918

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