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Indole derivatives. 131. The basicity of 5- and 6-aminoindoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The pKa values for the 5- and 6-aminoindoles were determined from potentiometric titration curves and from 13C NMR data on the total change of the chemical shifts of the carbon atom signals on protonation of the amino group. The pKa values obtained (5.99 and 5.53) were higher than those of aniline (3.92) or Β-naphthylamine (3.39).

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Authors and Affiliations

  1. D. I. Mendeleev Moscow Chemical-Technological Institute, 125047, Mosocw

    M. A. Salekh, L. N. Kurkovskaya, L. S. Krasavina, I. V. Persianova, M. M. Vigdorchik & N. N. Suvorov

  2. S. Ordzhonikidze, All-Union Scientific-Research Institute for Pharmaceutical Chemistry, 119815, Moscow

    M. A. Salekh, L. N. Kurkovskaya, L. S. Krasavina, I. V. Persianova, M. M. Vigdorchik & N. N. Suvorov

Authors
  1. M. A. Salekh
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  2. L. N. Kurkovskaya
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  3. L. S. Krasavina
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  4. I. V. Persianova
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  5. M. M. Vigdorchik
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  6. N. N. Suvorov
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Additional information

For Communication 130, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, 766–769, June, 1988.

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Salekh, M.A., Kurkovskaya, L.N., Krasavina, L.S. et al. Indole derivatives. 131. The basicity of 5- and 6-aminoindoles. Chem Heterocycl Compd 24, 624–627 (1988). https://doi.org/10.1007/BF00475595

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  • DOI: https://doi.org/10.1007/BF00475595

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