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Reduction of quinolinecarboxylic acids by raney alloy

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The heterocyclic nucleus in quinolinecarboxylic acids is reduced by Raney alloy (nickel-aluminium) in alkaline media to give 1,2,3,4-tetrahydro-2-,3-,4-,5-,6-, and 8-quinolinecarboxylic acids and 8-methyl-5-quinolinecarboxylic acid and their ethyl esters.

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Authors and Affiliations

  1. Institute of Biological and Medical Chemistry, Academy of Medical Sciences of the USSR, 119121, Moscow

    I. N. Graeheva & A. I. Tochilkin

Authors
  1. I. N. Graeheva
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  2. A. I. Tochilkin
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 77–79 January, 1988.

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Graeheva, I.N., Tochilkin, A.I. Reduction of quinolinecarboxylic acids by raney alloy. Chem Heterocycl Compd 24, 65–67 (1988). https://doi.org/10.1007/BF00475570

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  • DOI: https://doi.org/10.1007/BF00475570

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