Abstract
Dehydrogenation of 2-hydroxy-4-phenyl-3, 4, 5, 6-tetrahydrobenzo[h]quinazoline with Pd/C, diphenyl disulfide, chloranil, and N-bromosuccinimide, was investigated. Dihydroderivatives of 2-hydroxy-4-phenylbenzo[h]quinazoline were obtained. The action of N bromosuccinimide led to dehydrogenation and bromination. Treatment of 2-hydroxy-4-phenylbenzo[h]quinazoline and its bromine derivative with phosphorus oxychloride, followed by hydrogenation, gave 4-phenylbenzo[h]quinazoline. The structures of the compounds prepared are confirmed by spectroscopic data.
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Mamaev, V.P., Sedova, V.F. Pyrimidines. Chem Heterocycl Compd 1, 409–414 (1966). https://doi.org/10.1007/BF00473822
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DOI: https://doi.org/10.1007/BF00473822