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Synthesis and study of 2-(1-pyrazolyl)pyrimidine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Alkyl derivatives of 2-(1-pyrazolyl)-4(3H)-pyrimidinone were synthesized and converted to 4-chloro-, 4-arylamino-, and 4-hydrazino-2-(1-pyrazolyl)pyrimidines. The corresponding hydrazones were obtained by reaction of 5-ethyl-2-hydrazino-6-methyl-2-(4-ethyl-3,5-di-n-propylpyrazolyl) pyrimidine with isatin and salicylaldehyde. The UV and IR spectra of the synthesized compounds were studied. It was established that the hydrazones contain intra-molecular hydrogen bonds.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1255–1257, September, 1977.

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Ivashchenko, A.V., Dziomko, V.M. Synthesis and study of 2-(1-pyrazolyl)pyrimidine derivatives. Chem Heterocycl Compd 13, 1012–1014 (1977). https://doi.org/10.1007/BF00472461

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  • DOI: https://doi.org/10.1007/BF00472461

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