Abstract
3-Indolylalkanoic acids (III) were obtained from 3-acylindoles (I) under the conditions of the Willgerodt-Kindler reaction. The reactivity of I falls as the chain lengthens and 3-caproylindole does not undergo reaction. Removal of the carbonyl group away from the indole ring promotes the conversion of the ketones to III. Sulfur-containing compounds, the structure of which was studied, were isolated along with the intermediate products — thiomorpholides of indolylalkanoic acids (II).
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See [1] for communication LXXXIV.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 759–761, June, 1973.
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Avramenko, V.G., Shirnyuk, T.Y. & Suvorov, N.N. Indole derivatives. Chem Heterocycl Compd 9, 698–700 (1973). https://doi.org/10.1007/BF00472310
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DOI: https://doi.org/10.1007/BF00472310