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Synthesis of α-methyl- and α, γ-dimethylsubstituted thieno-, thionaphtheno-, and thienothienopyridines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

α-Methyl- and α,γ-dimethyl-substituted thieno-, thionaphtheno-, and thienothienopyridines, which are isosteres of quinaldine and benzoquinaldines, were synthesized by the condensation of the corresponding heterocyclic amines with paraldehyde via the Doebner-Miller reaction and with acetylacetone via the Combes method, respectively.

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Literature cited

  1. O. Doebner and W. Miller, Ber., 14, 2812 (1881).

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  2. W. S. Emerson, F. W. Holly, and L. H. Klemm, J. Am. Chem. Soc., 63, 2569 (1941).

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  3. V. G. Zhiryakov and P. I. Abramenko, Khim. Geterotsikl. Soedin., 334 (1965).

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Authors and Affiliations

  1. All-Union State Scientific-Research and Design Institute of the Photographic Chemical Industry, Moscow

    P. I. Abramenko

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  1. P. I. Abramenko
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 468–470, April, 1971.

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Abramenko, P.I. Synthesis of α-methyl- and α, γ-dimethylsubstituted thieno-, thionaphtheno-, and thienothienopyridines. Chem Heterocycl Compd 7, 436–438 (1971). https://doi.org/10.1007/BF00471479

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  • DOI: https://doi.org/10.1007/BF00471479

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