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Condensation of 2-amino-3-cyano-4,5,6,7-tetrahydroindole with Β-dicarbonyl compounds

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Depending on conditions, the condensation of 2-amino-3-cyano-4,5,6,7-tetrahydroindole with Β-dicarbonyl compounds leads to 2-methyl-4-oxo- or 4-methyl-2-oxo-10-cyano-6,7,8,9-tetrahydropyrimido[1,2-a]indoles via the intermediate compounds: 2-(3-ethoxy-carbonyl-prop-2-en-2-yl amino) and 2-(1,3-dioxobutylamino)-3-cyano-4,5,6,7-tetrahydroindoles, respectively.

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific Research Chemical Pharmaceutical Institute, 119815, Moscow

    M. V. Mezentseva, A. N. Grinev, O. S. Anisimova, L. M. Alekseeva & Yu. N. Sheinker

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  1. M. V. Mezentseva
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  2. A. N. Grinev
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  3. O. S. Anisimova
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  4. L. M. Alekseeva
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  5. Yu. N. Sheinker
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 833–838. June, 1989.

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Mezentseva, M.V., Grinev, A.N., Anisimova, O.S. et al. Condensation of 2-amino-3-cyano-4,5,6,7-tetrahydroindole with Β-dicarbonyl compounds. Chem Heterocycl Compd 25, 694–698 (1989). https://doi.org/10.1007/BF00470033

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  • DOI: https://doi.org/10.1007/BF00470033

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