Abstract
A method of synthesizing thiophene analogs of chalcone is described. It is based on condensation of chlorides of α, β-unsaturated acids with thiophene in the presence of an equimolecular amount of SnCl4 in benzene or toluene solution. Addition of 2-nitropropane at the active double bond of the thiophene analogs of chalcone gives γ-nitroketones.
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Belyaev, V.F., Abrazhevich, A.I. Synthesis and reactions of thiophene analogs of chalcone. Chem Heterocycl Compd 3, 653 (1967). https://doi.org/10.1007/BF00468336
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DOI: https://doi.org/10.1007/BF00468336