Summary
From a zeste mutant stock with a mutable white locus a new mutant (z w w) was isolated. It has a white-eyed phenotype and a short X-chromosome inversion (In(1)w w) which extends from salivary chromosome bands 3B2-C1 to 4B4-C1. In giant chromosomes of heterozygotes the inversion is unusually tightly paired. Probably because of this intimate pairing the recombination frequencies for regions near the inversion are not decreased in comparison to those for structurally normal chromosomes. The inversion chromosome is mutable. The mutations which arise have pigmented eyes and can be subdivided into two groups. One group is characterized by a re-inversion to normal chromosome structure. The mutability of the white locus appears to be independent of the inversion and reinversion. The process of reinversion is discussed.
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Literatur
Arcos-Terán, L., Beermann, W.: Changes of DNA replication behavior associated with intragenic changes of the white region in Drosophila melanogaster. Chromosoma (Berl.) 25, 377–391 (1968).
Becker, H. J.: Variegation in the zeste eye color alleles and its bearing on gene action during the development of the eye of Drosophila melanogaster. Genetics 45, 519–534 (1960).
Bridges, C. B.: Dros. Inf. Serv. 7, 11 (1937).
Gershenson, S.: The phenomenon of reinversion in the sex chromosome of Drosophila melanogaster. (Abstr.) IV. Syezd. Zool. Anat. Histol. 7 (1930).
—: A case of ClB reinversion. Dros. Inf. Serv. 1, 54 (1934).
Grüneberg, H.: A case of complete reversion of a chromosomal rearrangement in Drosophila melanogaster. Nature (Lond.) 138, 508 (1936).
Hoover, M. E.: Cytogenetic analysis of nine inversions in Drosophila melanogaster. Z. indukt. Abstamm.- u. Vererb.-L. 74, 420–434 (1938).
Kalisch, W.-E., Becker, H. J.: Über eine Reihe mutabler Allele des white-Locus bei Drosophila melanogaster. Molec. Gen. Genetics 107, 321–335 (1970).
Kaufmann, B. P.: Reversion from roughest to wild type in Drosophila melanogaster. Genetics 27, 537–549 (1942).
—: Organization of the chromosome. I. Break distribution and chromosome recombination in Drosophila melanogaster. J. exp. Zool. 102, 293–320 (1946).
Lefevre, G., Jr., Moore, B.: Recombination in regions adjacent to deletions in the X-chromosome of Drosophila melanogaster. Genetics 58, 557–571 (1967).
Lindsley, D. L., Grell, E. H.: Genetic variations of Drosophila melanogaster. Carnegie Inst. Wash. Publ. 627, (1968).
Morgan, L. V., Bridges, C. B., Sturtevant, A. H., Schultz, J.: Constitution of the germinal material in relation to heredity. Carnegie Inst. Wash. Year Book 36, 298–305 (1937).
Novitski, E.: The regular reinversion of the roughest 3 inversion. Genetics 46, 711–717 (1961).
Prokofyeva-Belgovskaya, A. A.: Cytological properties of inert regions and their bearing on the mechanisms of mosaicism and chromosome rearrangement. Dros. Inf. Serv. 15, 34–35 (1941).
—, Khvostova, V. V.: C. R. (Dokl.) Acad. Sci. URSS, N. S. 23, 269–271 (1939).
Redfield, H.: Recombination increase due to heterologous inversions and the relation to cytological length. Proc. nat. Acad. Sci. (Wash.) 41, 1084–1091 (1955).
Slizynski, B. H.: “Ectopic” pairing and the distribution of heterochromatin in the X-chromosome of salivary gland nuclei of Drosophila melanogaster. Proc. roy. Soc. Edinb. 62, 114–119 (1945).
Sturtevant, A. H., Beadle, G. W.: The relations of inversions in the X-chromosome of Drosophila melanogaster to crossing-over and disjunction. Genetics 21, 554–604 (1936).
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Kalisch, WE. Über eine mutable white-Inversion bei Drosophila melanogaster . Molec. Gen. Genet. 107, 336–350 (1970). https://doi.org/10.1007/BF00441195
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DOI: https://doi.org/10.1007/BF00441195