Summary
The origin and phenotypes of a number of zeste mutant stocks with mutable white loci are described. Each newly arising form was lighter in eye color than the mutant it originated from. In each case the lighter pigmentation is believed to be due to an increase in genetic material in the proximal region of the white locus, the increase supposedly being the result of unequal crossing over. Some of the mutations which arose in the mutable stocks are reversions. They occurred in males as well as in homo- and heterozygous females. The reversions are believed to be due to a decrease in genetic material in the proximal region of the white locus. The decrease is assumed to be the result of intrachromosomal recombination. At least some of these events took place premeiotically. New mutants which originate frequently from mutable stocks are stable. In addition to the structure of the mutable white locus there is probably at least one still unknown factor which affects its mutability since the frequency of mutations arising in the mutable stocks decreases over the years.
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Vorgelegt von C. Auerbach
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Kalisch, WE., Becker, H.J. Über eine Reihe mutabler Allele des white-Locus bei Drosophila melanogaster . Molec. Gen. Genet. 107, 321–335 (1970). https://doi.org/10.1007/BF00441194
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DOI: https://doi.org/10.1007/BF00441194