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A correlative assessment of photon interaction and histomorphometric measurements of bone density

  • Clinical and Experimental Forum
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Summary

Thirty-four femoral necks from human cadavers were measured by techniques assessing bone density and bone mineral density, and by the Singh index. These methods are based on photon interaction with biological components and can be applied noninvasively for clinical evaluation of changes in skeletal status. Trabecular bone volume, mineralized bone volume, and relative osteoid volume were evaluated histomorphometrically using undecalcified histologic sections obtained from the same samples. The trabecular and mineralized bone volumes showed significant correlations with the bone density and mineral density. These results enhance the validity of recently developed photoninteraction techniques for evaluating bone properties.

Zusammenfassung

Es wird über die Möglichkeit von nicht invasiven Untersuchungstechniken zur Bestimmung der Knochen- and Knochenmineraldichte berichtet. Diese Methoden basieren auf der Photonen-Interaktion mit biologischen Komponenten und kön-nnen eingesetzt werden, um Veränderungen des knöchernen Skelettes zu bewerten. Zur Untersuchung dienten 34 menschliche Leichenhüftköpfe. Die Ergebnisse wurden verglichen mit histomorphometrisch an unentkalkten Knochenschnitten der gleichen Proben ermittelten trabeculären Knochenvolumen, mineralisierten Knochenvolumen and relatives Osteoidvolumen. Es zeigte sich eine signifikante Korrelation zwischen trabeculärem and mineralisiertem Knochenvolumen mit der Knochen- und Mineraldichte. Diese Befunde erhöhen den Wert der kürz lich entwickelten Techniken der Photonen-Interaktion zur Bewertung von Knocheneigenschaften.

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Margulies, J.Y., Leichter, I., Robin, G.C. et al. A correlative assessment of photon interaction and histomorphometric measurements of bone density. Arch. Orth. Traum. Surg. 105, 239–242 (1986). https://doi.org/10.1007/BF00435489

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  • DOI: https://doi.org/10.1007/BF00435489

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