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Regulation of nitrile-hydratase synthesis in a Brevibacterium species

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Abstract

The regulation of nitrile-hydratase biosynthese was studied in Brevibacterium sp R 312. Enzyme biosynthesis was not influenced by any carbon and nitrogen source used in the growth medium. It was, however, repressed by amide and amide analogues. Acetamide repressed nitrile-hydratase biosynthesis and induced the wide-spectrum amidase. Therefore, it appeared reasonable to hypothesize a single repressor gene for the nitrile-hydratase/wide-spectrum amidase system.

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Authors and Affiliations

  1. Chaire de Génétique et Microbiologie, Ecole National Supérieure Agronomique de Montpellier, F-34060, Montpellier Cedex, France

    D. Tourneix, A. Thiéry, M. Maestracci, A. Arnaud & P. Galzy

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  1. D. Tourneix
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  2. A. Thiéry
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  3. M. Maestracci
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  4. A. Arnaud
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  5. P. Galzy
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Tourneix, D., Thiéry, A., Maestracci, M. et al. Regulation of nitrile-hydratase synthesis in a Brevibacterium species. Antonie van Leeuwenhoek 52, 173–182 (1986). https://doi.org/10.1007/BF00429321

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  • DOI: https://doi.org/10.1007/BF00429321

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