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Bioconversions of nitriles and their applications

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Advances in Biochemical Engineering, Volume 14

Part of the book series: Advances in Biochemical Engineering ((ABE,volume 14))

Abstract

The bioconversions of nitriles and primary amides have a practical interest for the production of optically active α-hydroxy — or α-amino acids and for the preparation of highly pure amides and acids. The appropriate chemical hydrolyses are generally not suitable for such syntheses.

The literature concerning the reactions of nitrile catabolism by living organisms is analyzed. Among these reactions, only hydrolyses are involved in industrial processes.

A large number of economically important products may be obtained by hydrolyzing nitriles or primary amides: acrylamide, lysergic acid, dl- or l-lactic acid, dl - or l-alanien, dl- or l-methionine, dl- or l-phenylalanine, and d- or l-phenylglycine, to name a few. The descriptions of the principal known processes and the possibilities for their improvement are presented and discussed.

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Authors and Affiliations

  1. Laboratoire de Chimie Organique, Université des Sciences et Techniques du Languedoc, F-34060, Montpellier Cedex, France

    Jean-Claude Jallageas

  2. Chaire de Génétique et Microbiologie Ecole Nationale Supérieure Agronomique, F-34060, Montpellier Cedex, France

    Alain Arnaud & Pierre Galzy

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  1. Jean-Claude Jallageas
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  2. Alain Arnaud
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  3. Pierre Galzy
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Jallageas, JC., Arnaud, A., Galzy, P. (1980). Bioconversions of nitriles and their applications. In: Advances in Biochemical Engineering, Volume 14. Advances in Biochemical Engineering, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0007187

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  • DOI: https://doi.org/10.1007/BFb0007187

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