Abstract
Serotonin infused through hepatic-portal cannulae of rabbits decreased food intake in a free-feeding condition. Following a 12 hr food deprivation period similar doses of serotonin increased food intake. Other investigators have shown release of serotonin to food and related stimuli. Our results demonstrate that serotonin is not a simple “satiety hormone” but suggest that it may be importantly involved in short-term regulatory mechanisms of feeding.
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Supported by NINDS grant No. NS 7687.
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Rezek, M., Novin, D. The effects of serotonin on feeding in the rabbit. Psychopharmacologia 43, 255–258 (1975). https://doi.org/10.1007/BF00429259
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DOI: https://doi.org/10.1007/BF00429259