Abstract
Destyrosine-γ-endorphin (DTGE) has purported neuroleptic properties, although the findings have been conflicting. Four chronic psychotic inpatients with neuroleptic-induced dyskinesias were treated with single injections of placebo and DTGE in high doses (20–120 mg). No consistent differences were found in tardive dyskinesia, parkinsonism, eye-blindking rates, or mental status. Laboratory tests were unchanged. It is concluded that acute DTGE treatment has no beneficial effect in drug-induced dyskinesia.
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Korsgaard, S., Casey, D.E. & Gerlach, J. High-dose destyrosine-γ-endorphin in tardive dyskinesia. Psychopharmacology 78, 285–286 (1982). https://doi.org/10.1007/BF00428167
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DOI: https://doi.org/10.1007/BF00428167