Abstract
Changes in mood after administration of Diazepam and Caffeine were analyzed. Six aspects were studied: pleasantness, activation, extraversion, calmness, social orientation and control. In addition to this check list, mood ratings using magnitude estimation of selected adjectives were obtained. It was found that Diazepam decreased feelings of activation and extraversion and increased calmness. Caffeine had no clear effects on the check list, but on the magnitude estimation scale some effects opposite to those of Diazepam were observed. Men reported a higher degree of pleasantness than women after administration of Diazepam. No differences in heart rate were found. Few distinct scale values were utilized on the magnitude estimation scale and the discriminative power was found to be larger for the check list than for the magnitude estimation scale.
Similar content being viewed by others
References
Cattell, R. B.: Personality and Mood Questionnaire. San Francisco: Jossey-Bass 1973
Cattell, R. B., Scheier, I. H.: The Meaning and Measurement of Neuroticism and Anxiety. New York: Ronald 1961
Danielsen, A., Haffner, J. F. W., Mørland, J., Setekleiv, J., Frivik, P. T., Strømsaether, C. E.: Effects of Diazepam and Ethanol on heart rate and galvanic skin responses. Acta Pharmacol. Toxicol. 36, 113–122 (1975)
Dixon, W. J., BMDP-Biomedical Computer Programs, University of California Press 1972
Duffy, E.: Activation. In: Handbook of Psychophysiology, N. S. Greenfield, R. A. Sternbach, eds., pp. 577–614. New York: Holt, Rinehart and Winston 1972
Ekman, G.: The measurement of subjective reactions. Försvarsmedicin 3, 27–41 (1967)
Frankenhauser, M., Sterky, K., Järpe, G.: Psychophysiological relations in habituation to gravitational stress. Percept. Mot. Skills 15, 63–72 (1962)
Green, R. F.: On the measurement of Mood, Technical Report No. 10, 1965. Rochester University, Research Project NR 171-342, Contract NO. 668 (12), Office of Naval Research.
Gunn, C. G., Wolf, S., Block, R. T., Person, R. J.: Psychophysiology of the cardiovascular system. In: Handbook of Psychophysiology, N. S. Greenfield, R. A. Sternbach, eds., pp. 457–483. New York: Holt, Rinehart and Winston 1972
Jäättelä, A., Määnistö, P., Paatero, H., Tuomisto, J.: The effects of Diazepam or Diphenhydramine on healthy subjects. Psychopharmacologia 21, 202–211 (1971)
Kelly, D., Pik, R., Chen, C.: A psychological and physiological evaluation of the effects of intravenous diazepam. Br. J. Psychiatry 122, 419–426 (1973)
Kolmodin, G.: Neurologiska indikationer. In: Symposium om Bensodiazepiner i relation till andra dagsedativa. G. Holmberg, ed., pp. 77–81. Stockholm: Roche AB 1974
Lienert, G. A., Huber, H. P.: Differential effects of coffee on speed and power test. Journal of Psychology 63, 269–274 (1966)
Lingjaerde, O.: Psykiatriske indikasjoner. In: Symposium om Bensodiazepiner i relation till andra dagsedativa. G. Holmberg, ed., pp. 65–70 Stockholm: Roche AB 1974
McNair, D. M., Lorr, M., Droppleman, L. F.: Profile of Mood States. San Diego: Educational and Industrial Testing Service 1971
Meddis, R. Bipolar factors in mood adjective check lists. Br. J. Soc. Clin. Psychol. 11, 178–184 (1972)
Nordlander, N. B.: Allmänmedicinska synpunkter. In: Symposium om Bensodiazepiner i relation till andra dagsedativa. G. Holmberg, ed., pp. 71–76. Stockholm: Roche AB 1974
Nowlis, V.: Methods for studying mood changes produced by drugs. Rev. Psychol. Appl. 11, 373–386 (1961)
Nowlis, V.: The concept of mood. In: Conflict and Creativity. S. M. Farber, R. H. Wilsen, eds., pp. 73–89. New York: McGraw-Hill 1963
Nowlis, V.: Research with the mood adjective check list. In: Affect, cognitions and personality. S. S. Tomkins, C. E. Izard, eds. Berlin-Heidelberg-New York: Springer 1965
Nowlis, V.: Moods: Behavior and experience. In: Feelings and emotions: The Loyola symposium. M. B. Arnold, ed., pp. 261–277. New York: Academic 1970
Nowlis, V., Nowlis, H. H.: The descriptions and analysis of mood. Ann. NY Acad. Sci. 65, 345–355 (1956)
Persson, L.-O., Sjöberg, L., Svensson E.: Mood effects of alcohol. Göteborg Psychol. Rep. 8, No. 4. (1978)
Ritchie, J. M.: Central nervous stimulants II. The xanthines. In: The pharmacological Basis of therapeutics. 4th edition. L. S. Goodman, A. Gilman, eds., pp. 358–370. New York: Macmillan 1970
Sjöberg, L., Svensson, E., Persson, L.-O.: The measurement of mood. Scand. J. Psychol. (in press) 1979
Svensson, E.: Response format and factor structure in mood adjective check lists. Scand. J. Psychol. 18, 71–78 (1977)
Werner, B.: Toxicitet och letalrisk. In: Symposium om Bensodiazepiner i relation till andra dagsedativa. G. Holmberg, ed., pp. 119–120. Stockholm: Roche AB 1974
Winer, B. J.: Statistical Principles in Experimental Design. New York: McGraw-Hill 1971
Wretlind, M., Pilbrant, Å., Sundwall, A., Vessman, J.: Disposition of three benzodiazepines after single oral administration in man. Stockholm: AB Kabi, Research Department 1977
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Svensson, E., Persson, LO. & Sjöberg, L. Mood effects of diazepam and caffeine. Psychopharmacology 67, 73–80 (1980). https://doi.org/10.1007/BF00427598
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00427598