Psychophysical investigations were carried out on patients with depressive and anxious-depressive disorders, including ECG, EEG, speech signal recordings, and testing of visuomotor reactions. Patients showed deterioration in measures of variational cardiometry relative to healthy subjects regardless of the presence or absence of anxiety syndrome. EEG dynamics during cognitive tests and the variability of the correlation dimension of the speech signal changed specifically in patients with anxiety syndrome. Increases in the standard deviation of the correlation dimension of the speech signal may provide an indicator of the presence of a depressive disorder, changes in the speech signal depending on the type of depressive disorder.
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Asada, H., Fukuda, Y., Tsunoda, S., Yamaguchi, M., and Tonoike, M., “Frontal midline theta rhythms refl ect alternative activation of prefrontal cortex and anterior cingulate cortex in humus,” Neurosci. Lett., 274, No. 1, 29–32 (1999).
Baevskii, R. M., Mathematical Analysis of Changes in Heart Rhythm during Stress, Nauka, Moscow (1984).
Bazanova, O. M., “Current interpretation of EEG α activity,” Usp. Fiziol. Nauk., 3, 32–53 (2009).
Billman, G. E., “The LF/HF ratio does not accurately measure cardiac sympathovagal balance,” Front. Physiol., (2013).
Bokeriya, P. A., Bokeriya, O. L., and Volkovskaya, I. V., “Heart rhythm variability: measurement methods, interpretation, clinical utilization,” Annaly Aritmol., 4, 21–32 (2009).
Fingelkurts, A. A. and Fingelkurts, A. A., “Altered structure of dynamic electroencephalogram oscillatory pattern in major depression,” Biol. Psychiatry, 77, No. 12, 1050–1060 (2015).
Gudkov, G. V., Antenatal Cardiotocography in Reducing Perinatal Losses: Auth. Abstr. Doctoral Thesis in Medical Sciences, MX (2010).
Hegger, R., and Kantz, H., “Practical implementation of nonlinear time series methods: The TISEAN package,” Chaos, 9, 413–435 (1999).
Hirschfeld, R. M. A., “The comorbidity of major depression and anxiety disorders,” Prim. Care Companion J. Clin. Psychiatry, 3, No. 6, 244–254 (2001).
Kapfhammer, H., “Somatic symptoms in depression,” Dialogues Clin. Neurosci., 8, No. 2, 227–239 (2006).
Klimesch, W., “EEG alpha and theta oscillations refl ect cognitive and memory performance: a review and analysis,” Brain Res. Rev., 29, 169–176 (1999).
Klimesch, W., Sauseng, P., and Hanslmayr, S., “EEG alpha oscillations: the inhibition-timing hypothesis,” Brain Res. Rev., 53, 63–88 (2007).
Krishnan, V. and Nestler, E. J., “The molecular neurobiology of depression,” Nature, 455, No. 7215, 894–902 (2008).
Nikolaeva, D. A., “Use of a method for evaluating correlation dimension for analysis of the EEG of people with epilepsy,” Differentsial. Uravn. Protsess. Upravl. (electronic journal) No. 2 (2009).
Olshansky, B., Sabbah, H. N., Hauptman, P. J., and Colucci, W. S., “Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy,” Circulation, 118, No. 8 (2008).
Raghavachari, S., Kahana, M. J., Rizzuto, D. S., Caplan, J. B., Kirschen, M. P., Bourgeois, B., Madsen, J. R., and Lisman, J. E., “Gating of human theta oscillations by a working memory task,” J. Neurosci., 21, No. 9, 3175–3183 (2001).
Ruttkai-Nedetski, I., “Challenges in the electrocardiological evaluation of the infl uences of the autonomic nervous system on the heart,” Vestn. Aritmol., 22, 56–60 (2001).
Sasaki, K., Tsujimoto, T., Nishikawa, S., Nishitani, N., and Ishihara, T., “Frontal mental theta wave recorded simultaneously with magnetoencephalography and electroencephalography,” Neurosci. Res., 26, No. 1, 79–81 (1996).
Savostianov, A. N., Dolgorukova, T. A., Esipenko, E. A., Zaleshin, M. S., Malanchini, M., Budakova, A. V., Saprygin, A. E., and Kovas, Y., “The impact of trait and mathematical anxiety on oscillatory brain activity during lexical and numerical error-recognition tasks,” WASET Ling. Lang. Sci., 2, No. 7, 285 (2015).
Shao, J., MacCallum, J. K., Zhang Y, Sprecher, A., and Jiang, J. J., “Acoustic analysis of the tremulous voice: assessing the utility of the correlation dimension and perturbation parameters,” J. Commun. Disord., 43, No. 1, 35–44 (2010).
Smulevich, A. B. and Dubnitskaya, E. B., “Anxious depression,” Med. Gazeta, No. 2 (2004).
Zharikov, N. M. and Tyul’pin, Yu. G., Psychiatry, Medical Information Agency (2002).
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Translated from Zhurnal Vysshei Nervnoi Deyatel’nosti imeni I. P. Pavlova, Vol. 67, No. 3, pp. 288–298, May–June, 2017.
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Kazimirova, E.A., Grishkina, M.N. & Lebedeva, N.N. Psychophysical Characteristics of Patients with Depression and Anxious-Depressive Disorders. Neurosci Behav Physi 48, 983–989 (2018). https://doi.org/10.1007/s11055-018-0659-4
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DOI: https://doi.org/10.1007/s11055-018-0659-4